Search results for "Respiratory failure"

showing 10 items of 110 documents

Early and rapidly progressing respiratory failure in a patient with amyotrophic lateral sclerosis: when FVC% is misleading

2018

Introduction Respiratory failure is the leading cause of death in amyotrophic lateral sclerosis (ALS) [1]. The involvement of respiratory function is a negative predictor of survival, which can be in part overcome by a prompt initiation of non-invasive mechanical ventilation (NIV). Seated forced vital capacity (FVC%) is a widely used measure to monitor respiratory function, and it is often taken as a surrogate outcome measure in clinical trials. However, it may be within a normal range in ALS patients with respiratory dysfunction [2]. Here we report on a case of an ALS patient with a rapidly evolving respiratory insufficiency, despite a rather normal FVC%. Case presentation The patient, a 6…

0301 basic medicineMalePediatricsmedicine.medical_specialtyNeurologyDermatologyDiagnosis Differential03 medical and health sciencesFEV1/FVC ratio0302 clinical medicineFatal OutcomeMedicineAmyotrophic lateral sclerosisNeuroradiologyAgedbusiness.industryDisease progressionGeneral Medicinemedicine.diseasePsychiatry and Mental health030104 developmental biology030228 respiratory systemRespiratory failureDisease ProgressionNeurology (clinical)NeurosurgeryDifferential diagnosisbusinessRespiratory InsufficiencyAmyotrophic Lateral SclerosiHuman
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Epidemiologic and Clinical Characteristics of Coronavirus and Bocavirus Respiratory Infections after Allogeneic Stem Cell Transplantation: A Prospect…

2018

Highlights • Human coronavirus are common after allogeneic stem cell transplantation and can progress to LRTDs, and in some cases this leads to hospitalization and requires supportive care. • Human bocavirus are quite rare after allogeneic stem cell transplantation and are commonly detected in conjunction with other viral co-pathogens.

0301 basic medicineMalevirusesBocavirus Community-acquired respiratory virusmedicine.disease_cause0302 clinical medicineHuman bocavirus030212 general & internal medicineProspective StudiesRespiratory Tract InfectionsCoronavirusRespiratory tract infectionsbiologyHuman bocavirusHematopoietic Stem Cell Transplantationvirus diseasesHematologyMiddle AgedAllograftsHospitalizationViral pneumoniaRespiratory virusFemaleCoronavirus InfectionsAdultmedicine.medical_specialtyViral pneumonia030106 microbiologyContext (language use)ArticleParvoviridae InfectionsBocavirus03 medical and health sciencesCommunity-acquired respiratory virusInternal medicinemedicineHumansAgedTransplantationbusiness.industrymedicine.diseasebiology.organism_classificationVirologyrespiratory tract diseasesAllogeneic stem cell transplantationTransplantationCoronavirusRespiratory failureRespiratory virus infectionbusinessFollow-Up Studies
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The Culpability of Respiratory Viruses in Pneumonia-Related Acute Respiratory Failure

2018

0301 basic medicinePulmonary and Respiratory Medicinemedicine.medical_specialtybusiness.industrymedia_common.quotation_subject030106 microbiologyMEDLINECritical Care and Intensive Care Medicinemedicine.disease03 medical and health sciencesPneumonia0302 clinical medicineJurymedicineAcute respiratory failure030212 general & internal medicineRespiratory systemCardiology and Cardiovascular MedicineIntensive care medicinebusinessmedia_commonCulpabilityChest
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Noninvasive ventilation for acute hypoxemic respiratory failure/ARDS: The show must go on

2018

0301 basic medicinemedicine.medical_specialtyARDSAcute hypoxemic respiratory failureEmergency Medicine; Anesthesiology and Pain Medicinebusiness.industryNon-invasive ventilation in hypoxemic respiratory failure/ards | GREGORETTI CORTEGIANI RAINERI GIARRATANO VS. HILL GARPESTAD SCHUMAKER SPOLETINImedicine.disease03 medical and health sciences030104 developmental biologyAnesthesiology and Pain MedicineEmergency MedicineMedicineNoninvasive ventilationbusinessIntensive care medicine
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Use of autobilevel ventilation in patients with obstructive sleep apnea: An observational study.

2017

Continuous positive airway pressure (CPAP) is the first-choice treatment for obstructive sleep-disordered breathing. Automatic bilevel ventilation can be used to treat obstructive sleep-disordered breathing when CPAP is ineffective, but clinical experience is still limited. To assess the outcome of titration with CPAP and automatic bilevel ventilation, the charts of 356 outpatients (obstructive sleep apnea, n = 242; chronic obstructive pulmonary disease + obstructive sleep apnea overlap, n = 80; obesity hypoventilation syndrome [OHS], n = 34; 103 females) treated for obstructive sleep-disordered breathing from January 2014 to April 2017 were reviewed. Positive airway pressure titration was …

AdultMaleCognitive Neurosciencemedicine.medical_treatmentAmbulatory managementRespiratory failureSettore MED/10 - Malattie Dell'Apparato RespiratorioBody Mass Index03 medical and health sciencesBehavioral Neuroscience0302 clinical medicinePositive airway pressuremedicineNon-invasive ventilationHumansContinuous positive airway pressureAgedRetrospective StudiesObesity hypoventilation syndromeSleep Apnea ObstructiveContinuous Positive Airway Pressurebusiness.industryGeneral MedicineMiddle Agedmedicine.diseaseRespiration ArtificialConfidence intervalrespiratory tract diseasesObstructive sleep apnea030228 respiratory systemRespiratory failureAnesthesiaNon-invasive ventilationBreathingPatient ComplianceFemalebusiness030217 neurology & neurosurgeryFollow-Up StudiesJournal of sleep research
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Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis o…

2018

Background: Diabetes mellitus is a common co-existing disease in the critically ill. Diabetes mellitus may reduce the risk of acute respiratory distress syndrome (ARDS), but data from previous studies are conflicting. The objective of this study was to evaluate associations between pre-existing diabetes mellitus and ARDS in critically ill patients with acute hypoxemic respiratory failure (AHRF). Methods: An ancillary analysis of a global, multi-centre prospective observational study (LUNG SAFE) was undertaken. LUNG SAFE evaluated all patients admitted to an intensive care unit (ICU) over a 4-week period, that required mechanical ventilation and met AHRF criteria. Patients who had their AHRF…

AdultMaleDiabetes mellituLUNG SAFEOrgan Dysfunction Scoreshumanoslnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]Socio-culturaleOrgan Dysfunction ScoreDiabetes ComplicationsDiabetes mellituspuntuaciones de disfunción orgánicaRisk FactorsDiabetes Complicationestudios prospectivosHumansfactores de riesgoProspective StudiesHospital MortalityHypoxiamediana edadAcute hypoxemic respiratory failureAgedRespiratory Distress SyndromeancianoAcute respiratory distress syndromeResearchRespirationrespiraciónRespiratory Distress Syndrome Adultlcsh:Medical emergencies. Critical care. Intensive care. First aidlcsh:RC86-88.9Middle AgedRespiration Artificialinsuficiencia respiratoriaAcute hypoxemic respiratory failure; Acute respiratory distress syndrome; Diabetes mellitus; LUNG SAFEProspective StudieArtificialAcute hypoxemic respiratory failure; Acute respiratory distress syndrome; Diabetes mellitus; LUNG SAFE; Aged; Diabetes Complications; Diabetes Mellitus; Female; Hospital Mortality; Humans; Hypoxia; Male; Middle Aged; Organ Dysfunction Scores; Prospective Studies; Respiration Artificial; Respiratory Distress Syndrome Adult; Respiratory Insufficiency; Risk FactorsFemaleRespiratory Insufficiencymortalidad hospitalariacomplicaciones de la diabetesHuman
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Tidal Volume Estimation during Helmet Noninvasive Ventilation: an Experimental Feasibility Study

2019

AbstractWe performed a bench (BS) and human (HS) study to test the hypothesis that estimation of tidal volume (VT) during noninvasive helmet pressure support ventilation (nHPSV) would be possible using a turbine driven ventilator (TDV) coupled with an intentional leak single-limb vented circuit. During the BS a mannequin was connected to a lung simulator (LS) and at different conditions of respiratory mechanics, positive end expiratory pressure (PEEP) levels and leaks (30, 50 and 80 L/min). All differences were within the 95% limits of agreement (LoA) in all conditions in the Bland-Altman plot. The overall bias (difference between VT measured by TDV and LS) was 35 ml (95% LoA 10 to 57 ml), …

AdultMaleLeakmedicine.medical_specialtylcsh:MedicineSettore MED/41 - AnestesiologiaPressure support ventilationTherapeuticsRespiratory physiologyManikinsArticlePositive-Pressure Respiration03 medical and health sciences0302 clinical medicineInternal medicineHealthy volunteersTidal VolumemedicineHumanslcsh:SciencePositive end-expiratory pressureTidal volumeMouthpieceVentilators Mechanicalacute respiratory failureMultidisciplinarybusiness.industrylcsh:RhelmetReproducibility of Resultsnoninvasive ventilation030208 emergency & critical care medicineEquipment DesignHealthy Volunteers030228 respiratory systemPreclinical researchRespiratory MechanicsCardiologyFeasibility Studieslcsh:QFemaleHead Protective DevicesNoninvasive ventilationbusinessScientific Reports
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Effects of corticotropin-releasing hormone on respiratory parameters during sleep in normal men.

2009

Corticotropin-releasing hormone (CRH) is well-known to be a centrally acting respiratory stimulant after systemic application both in healthy subjects and in patients suffering from respiratory failure. In order to study the effects of CRH on sleep EEG and respiratory parameters during sleep, 14 healthy male volunteers were investigated in a single-blind placebo controlled design. After an adaptation night, polysomnography was performed during two successive nights between 23.00 hrs. and 7.00 hrs. During one night placebo was applied, on the other 50 μg ovine CRH was administered intravenously as a bolus every hour from 0.00 hrs. to 6.00 hrs. For the assessment of respiration, blood oxygen …

AdultMaleendocrine systemmedicine.medical_specialtyHydrocortisoneCorticotropin-Releasing HormoneEndocrinology Diabetes and MetabolismSleep REMPolysomnographyPlacebosCorticotropin-releasing hormoneEndocrinologyAdrenocorticotropic HormoneDouble-Blind MethodSleep and breathingInternal medicineInternal MedicinemedicineHumansRespiratory systemTidal volumeSlow-wave sleepmedicine.diagnostic_testbusiness.industryElectromyographyRespirationElectroencephalographyGeneral MedicineThoraxOxygenKineticsEndocrinologyRespiratory failureAnalepticAnesthesiabusinessSleephormones hormone substitutes and hormone antagonistsExperimental and clinical endocrinologydiabetes : official journal, German Society of Endocrinology [and] German Diabetes Association
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Sex difference and intra-operative tidal volume: Insights from the LAS VEGAS study

2021

BACKGROUND: One key element of lung-protective ventilation is the use of a low tidal volume (V(T)). A sex difference in use of low tidal volume ventilation (LTVV) has been described in critically ill ICU patients. OBJECTIVES: The aim of this study was to determine whether a sex difference in use of LTVV also exists in operating room patients, and if present what factors drive this difference. DESIGN, PATIENTS AND SETTING: This is a posthoc analysis of LAS VEGAS, a 1-week worldwide observational study in adults requiring intra-operative ventilation during general anaesthesia for surgery in 146 hospitals in 29 countries. MAIN OUTCOME MEASURES: Women and men were compared with respect to use o…

AdultMalemedicine.medical_specialtyIntra operativehealth care facilities manpower and services[SDV]Life Sciences [q-bio]Critical IllnessLas Vegas StudyArticle03 medical and health sciences0302 clinical medicine030202 anesthesiologyInternal medicineTidal VolumemedicineHumansGeneral anaesthesiaLungTidal volumeAdult; Critical Illness; Female; Humans; Lung; Male; Tidal Volume; Respiration Artificial; Sex CharacteristicsSex CharacteristicsLas vegasbusiness.industryRespirationrespiratory failure sexrespiratory systemSex differenceRespiration Artificialrespiratory tract diseasesAnesthesiology and Pain Medicine030228 respiratory systemRelative riskArtificialCohortBreathingFemaleObservational studybusinessintra-operative tidal volumecirculatory and respiratory physiology
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Noninvasive ventilation in chest trauma: systematic review and meta-analysis

2013

Purpose: Single studies of Noninvasive Ventilation (NIV) in the management of acute respiratory failure in chest trauma patients have produced controversial findings. The aim of this study is to critically review the literature to investigate whether NIV reduces mortality, intubation rate, length of stay and complications in patients with chest trauma, compared to standard therapy. Methods: We performed a systematic review and meta-analysis of randomized controlled trials, prospective and retrospective observational studies, by searching PubMed, EMBASE and bibliographies of articles retrieved. We screened for relevance studies that enrolled adults with chest trauma who developed mild to sev…

AdultRiskmedicine.medical_specialtyThoracic Injuriesmedicine.medical_treatmentMEDLINEChest traumaAcute respiratory failureCritical Care and Intensive Care MedicineAnesthesiologyIntubation IntratrachealmedicineHumansIntubationMeta-analysiIn patientAcute respiratory failureHospital MortalityIntensive care medicineOutcomeNoninvasive VentilationThoracic Injuriebusiness.industryLength of StayTreatment OutcomeMeta-analysisNoninvasive ventilationRespiratory InsufficiencybusinessStandard therapyHumanIntensive Care Medicine
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